Product Name:Acetyl-Amyloid Beta/A4 Protein Precursor770 (96-110) (cyclized)
Synonym: Ac-APP770 (96-110) (cyclized)
Sequence(three-letter):Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH2 (Disulfide bond)
Molecular Formula: C81H128N32O19S2
Application / Models
This product is for research only, not for human use.
References: D.H.Small et al., J. Neurosci., 14, 2117 (1994)
Illustration:This cyclized peptide which is homologous to the heparin-binding domain of APP, binds strongly to heparin and inhibits binding of 125I-labeled APP to heparin (IC50= 10-7M). The peptide blocks the heparan sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.
Condition Of Storage: -20 u00b1 5 u00b0C
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