HA is major components in human stromal cells,
vitreous, synovial fluid and other connective tissue in
the body HA plays an important role in retaining
water, maintain extracellular space, adjusting
osmotic pressure, lubricating and improving cells
As a major components of intercellular
substance, HA directly takes part in electrolyte
alternate control between cells and exerts the
function of message filter of physics and molecule.
High molecular HA can restrain the movement,
multiplication and phagocytosis of cells while low
molecular HA plays a role of stimulation.
HA has unique physicochemical properties and
physiological functions. It has been widely applied
in the pharmaceutical industry. HA can be used as
viscoelastic materials in intraocular lens implantation
and as fillers in articular surgery against
osteoarthritis, rheumatoid arthritis etc. It is also used
as medium in eye drops extensively.
Furthermore, HA is helpful in preventing post-
surgery conglutination and improving wound
healing. The compound as a result of its reaction to
other medicine may play a role of sustained release,
thus achieving the purpose of targeted and timed
release. With the development of medical science,
HA will become more and more useful in the field of
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